Search on: TUMOR NECROSIS FACTORS 
Descriptors Found: 1
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Descriptor English:   Tumor Necrosis Factors 
Descriptor Spanish:   Factores de Necrosis Tumoral 
Descriptor Portuguese:   Fatores de Necrose Tumoral 
Synonyms English:   TNF  
Tree Number:   D12.644.276.374.750
D12.644.276.972
D12.776.467.374.750
D12.776.467.972
D23.529.374.750
D23.529.972
Definition English:   A family of proteins that were originally identified by their ability to cause NECROSIS of NEOPLASMS. Their necrotic effect on cells is mediated through TUMOR NECROSIS FACTOR RECEPTORS which induce APOPTOSIS. 
History Note English:   2005 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists antagonists & inhibitors
analysis biosynthesis
blood cerebrospinal fluid
chemistry classification
chemical synthesis contraindications
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
urine  
Record Number:   38737 
Unique Identifier:   D048069 

Occurrence in VHL: 		 

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